is butoxyethanol toxic


Overview. SCA endorses products with the Toxic-Free Tick, that do not contain butoxyethanol CAS 111-76-2. “2-Butoxyethanol is readily absorbed following inhalation, oral, and dermal exposure. How likely is 2-butoxyethanol and 2-butoxyethanol acetate to cause cancer? Cosmetic products such as hair dyes, nail polishes, nail polish removers and skin cleansers contain butoxyethanol, which can help prevent the other product ingredients from separating within the formulation. Note: Javascript is disabled or is not supported by your browser. Print this Page. Compare Products: Select up to 4 products. Acute Tox. When tested undiluted, 2-butoxyethanol is a severe eye irritant (CICAD 1998). As with other cleaning products, keep household products containing 2-butoxyethaol out of the reach of children to avoid accidental ingestion. The safety of Butoxyethanol has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel. From all the studies, no specific relevant toxic effects, other that haemotoxicity, can be identified that are clearly related to treatment with 2 -butoxyethanol. U.S. Agency for Toxic Substances & Disease Registry, U.S. Occupational Safety and Health Administration. These compounds enhance the dispersion of oil by reducing … [1] [3] It is also associated with asthma and allergies. 2-Butoxyethanol is a colorless liquid with a mild odor. You can normally find 2-Butoxyethanol in window and kitchen cleaners. 2-Butoxyéthanol France (VLEP contraignante) 10 49 50 246 2-Butoxyéthanol Allemagne (valeurs MAK) 10 49 - - 2-Butoxyéthanol États-Unis (ACGIH) 20 97 - - Méthodes de détection et de détermination dans l'air Intermédiaire de synthèse organique, notamment pour la fabrication de l'acétate de 2-butoxyéthyle. Has the federal government made recommendations to protect human health? Based on the National Pollutant Release Inventory (NPRI), most reported environmental releases are to the atmosphere, with some minor releases to water. This toxic chemical is mainly found in the kitchen, in glass and multi-purpose cleaners. HP6 Acute Toxicity: waste which can cause acute toxic effects following oral or dermal administration, or inhalation exposure. Because this product can work as a surfactant, it is able to … The National Emission Standards for Hazardous Air Pollutants regulates 2-butoxyethanol under the Clean Air Act because it has demonstrated the potential to cause serious health issues including reduced fertility, low birth weight and toxic liver metabolites. 2-Butoxyethanol is not currently produced in Canada. down in air into other compounds within a few days. Common household cleaning products like glass cleaners, liquid soaps and all-purpose spray-cleaners contain butoxyethanol, for its ability to help dissolve substances such as grease and dirt. D'après l'Inventaire national des rejets de polluants (INRP), la plupart des rejets déclarés dans l'environnement se font vers l'atmosphère, hormis quelques rejets dans l'eau. What happens to 2-butoxyethanol and 2-butoxyethanol acetate when it enters the environment? According to the U.S. Agency for Toxic Substances & Disease Registry (ATSDR), inappropriately or accidentally swallowing large amounts of cleaning agents containing butoxyethanol can cause harmful effects for people. Sutton explains: “Our concern is daily, weekly, chronic exposure over a lifetime. Those could include breathing problems, low blood pressure, lowered levels of hemoglobin, blood in the urine, and metabolic acidosis (high levels of acid in the body). Since it is significantly less toxic as compared to ethylene glycol, propylene glycol is the preferred antifreeze used in motor homes and recreational vehicles. NOTE! 2-Butoxyethanol (C ₄ H ₉ OCH ₂ CH ₂ OH) is a colorless liquid with a mild odor. According to the U.S. Agency for Toxic Substances & Disease Registry (ATSDR), inappropriately or accidentally swallowing large amounts of cleaning agents containing butoxyethanol can cause harmful effects for people. 2-Butoxyethanol increases hemangiosarcomas selectively in male mouse liver after chronic inhalation through mechanisms that have not fully been elucidated. For risk characterisation purposes therefore, haemotoxicity will be the end point chosen keeping in mind the interspecies differences (human/rodents) to calculate margin of safety. The CIR Expert Panel reviewed the scientific data and concluded that Butoxyethanol is safe in hair and nail products at concentrations up to 10.0%. The EPA has identified this chemical as especially hazardous when inhaled. 2-Butoxyethanol is not currently produced in Canada. furniture production and finishing, spray-painting operations, The dispersant COREXIT 9527 contains propylene glycol, 2-butoxyethanol, and dioctyl sodium sulfosuccinate. No studies have been found that tested butoxyethanol for causing cancer in animals, according to ATSDR. A colorless liquid with a sweet scent, butoxyethanol is primarily used in paints and coatings, and also is an ingredient some household cleaning products, cosmetics and personal care products. 2-Butoxyethanol. Manifestations of acute butoxyethanol toxicity include metabolic acidosis, hemolysis, hepatorenal dysfunction, and coma, but vary widely in reported cases. be removed by rain, ice, or snow. HP4 Irritant — skin irritation and eye damage: waste which on application can cause skin irritation or damage to the eye. Print It's used a a solvent in paint strippers, thinners. Learn more about the chemistry in the products we rely on every day, including how and why particular chemicals are used in different products, and health and safety information about these chemicals. 2010. According to ATSDR, inappropriately or accidentally swallowing large amounts of cleaning agents containing butoxyethanol can cause harmful effects. In COREXIT 9500 the toxic 2-butoxyethanol was replaced with light petroleum distillate. Breathing in large amounts of 2-butoxyethanol or 2-butoxyethanol acetate may result in irritation of the nose and eyes, headache, and vomiting. low U.S. Environmental Protection Agency. On importe le 2-butoxyéthanol pour utilisation comme ingrédient de formulations, de produits de consommation ou d'articles fabriqués, ainsi que comme adjuvant de traitements chimiques. For using cleaning products containing butoxyethanol in the home, follow safe handling instructions included on the label to minimize potential exposure. Some harmful effects of 2-butoxyethanol have been seen in animals such as rats and rabbits. Is there a medical test to show whether I've been exposed to 2-butoxyethanol and 2-butoxyethanol acetate? Working in occupations such as silk-screening, printing, and 2-butoxyethanol acetate every day. To help protect workers who use butoxyethanol in occupational settings, the U.S. Occupational Safety and Health Administration (OSHA) has set an exposure limit of 50 parts of 2-butoxyethanol per million parts of air (50 ppm) for an 8-hour workday, 40-hour workweek. Though it can also be found in household cleaners. Use the search box to find information on the chemicals that are essential to the products you use every day. 2-Butoxyethanol is a clear colorless liquid that smells like ether. 2-Butoxyethanol and 2-butoxyethanol acetate may break Exposures near the lethal level caused systemic toxicity in the form of hemoglobinuria and lung, kidney, and liver changes. Exposure to 2-butoxyethanol and butoxyethanol acetate occurs mainly from breathing air or having skin contact with household products containing them. For this reason, some items on this page will be unavailable. This chemical is known by many different names, which are a mouthful, to say the least. Many people are exposed to small amounts of 2-butoxyethanol Butoxyethanol was only slightly toxic in an acute oral study in rats and in a dermal study in rabbits. How can 2-butoxyethanol and 2-butoxyethanol acetate affect my health? 2-Butoxyethanol Petroleum Uses This product is an essential component of fracturing fluids, drilling stabilizers, and oil slick dispersants for water-based and oil-based hydraulic fracturing. Other glycol ethers, such as EGME/EGBE, are a group of compounds that are used as organic solvents in various products. Butoxyethanol is also regulated under the Clean Air Act, including the National Emission Standards for Hazardous Air Pollutants. Use restrictions (moderate), Non-reproductive organ system toxicity (low), Irritation (skin, eyes, or lungs) (high), and Occupational hazards (high) fragrance ingredient, solvent, viscosity decreasing agent, masking, and viscosity controlling Butoxyethanol is an ether alcohol. Skin irritation. Eye irritation. Maybe if you’re exposed to a chemical a handful of times it wouldn’t cause harm, but some chemicals build up enough or cause enough harm in your body over time that it triggers some kind of disease outcome. Other reproductive effects and birth defects in animals have only been observed at doses that were toxic to the adult animals." Both compounds may pass into air from water and soil. How might I be exposed to 2-butoxyethanol and 2-butoxyethanol acetate? For more information about this message, please visit this page: Agency for Toxic Substances & Disease Registry, 2-Butoxyethanol and 2-Butoxyethanol Acetate. Butoxyethanol was nephrotoxic in an intravenous study in rats, but not when administered intraperitoneally. Butoxyethanol also can help keep a substance clear—even after a product is exposed to extreme temperatures during shipping or storage. One of the main industrial uses of butoxyethanol is as a solvent in protective surface coatings, such as spray lacquers, quick-dry lacquers and enamels, as well as water-based varnishes and latex paints. 111-76-2. 1-3, p. 71). You may have seen 2-Butoxyethanol as Ethylene Glycol Monobutyl Ether, Butyl Glycol, Butyl Oxitol, or Glycol Butyl Ether and more. It is advertised as an environmentally friendly, non-toxic, and biodegradable cleaner. 4 Skin Irrit. Diethylene glycol is used in numerous products including solvents and brake fluids. No evidence of genotoxicity was seen in a battery of tests with metabolic activation, but positive and negative effects were seen in the absence of metabolic activation. Butoxyethanol is also an ingredient in adhesives and inks used on food packaging. 2-Butoxyethanol in the environment comes from some industrial activities. 2-Butoxietanol The level of exposure depends upon the dose, duration, and work being done. 2-Butoxyethanol. 2-Butoxyethanol - Identification, toxicity, use, water pollution potential, ... PAN Bad Actors are chemicals that are one or more of the following: highly acutely toxic, cholinesterase inhibitor, known/probable carcinogen, known groundwater pollutant or known reproductive or developmental toxicant. or other liquids that contain these compounds. 2-butoxyethanol and 2-butoxyethanol acetate. The CIR found that even at the maximum concentration of 10 percent, water-based butoxyethanol did not cause skin irritation in a patch test involving 201 subjects. This is the compound that gives many cleaners a sweet smell. Cleaning products with butoxyethanol can be effective in cleaning grease and dirt, and can be used safely by following instructions on a product’s label. 2-Butoxyethanol … Exposures to butoxyethanol are more likely to occur in the workplace, for example in spray-painting operations or automobile repair shops, rather than in the environment or at home. 2-Butoxyethanol has moderate acute toxicity and is irritating to the eyes and skin; it is not a skin sensitizer.” Read more: Understanding Risk and Hazard When it Comes to Chemicals, butoxyethanol is safe in hair and nail products, U.S. Agency for Toxic Substances & Disease Registry (ATSDR). and 2-butoxyethanol acetate are disposed of. It is usually produced by a reaction of ethylene oxide with butyl alcohol, but it may also be made by the reaction of ethylene glycol with dibutyl sulfate. 2-Butoxyethanol was identified as a causal agent in the health problems experienced by cleanup workers after the 1989 Exxon Valdez oil spill. 2-butoxyethanol; ethyleneglycol monobutyl ether; butyl cellosolve. It has many names including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellusolve, butyl glycol, and butyl Oxitol. Living near a hazardous waste site where 2-butoxyethanol 2-Butoxyethanol and 2-butoxyethanol acetate may be released 111-76-2) are rare despite the prevalence of this glycol ether in products such as glass and surface cleaners. Those could include breathing problems, low … Don’t use Butyl Cellosolve. Toxic substances list: 2-butoxyethanol. 2. recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances. As a relatively nonvolatile, inexpensive solvent, it is used in many domestic and industrial products because of its properties as a surfactant. It is a known respiratory irritant and can be acutely toxic but animal studies did not find it to be mutagenic, and no studies suggest it is a human … *Please select more than one item to compare 2-Butoxyethanol and 2-butoxyethanol acetate do not build Butoxyethanol helps decrease the overall thickness of a varnish or paint to help enable smoother application. ATSDR can also tell you the location of occupational and environmental health clinics. A U.S. Environmental Protection Agency review finds 2-butoxyethanol is not toxic to reproduction or development. Butyl Cellosolve (CAS #111-76-2 also known as Butyl Cellusolve, Butoxyethanol, Butyl Glycol and Ethylene Glycol Monobutyl Ether) is a toxic agent used in many industrial and domestic cleaners – many of which claim to be non-hazardous.It is absorbed through the skin and lungs causing a variety of health issues depending on the level of exposure. This toxic body burden is EWG’s chief concern about household chemicals. In air, 2-butoxyethanol and 2-butoxyethanol acetate may products. How to avoid 2-Butoxyethanol Chemsrc provides 2-butoxyethanol(CAS#:111-76-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. As the Centers for Disease Control and Prevention notes, exposure to 2-Butoxyethanol can harm your eyes, skin, kidneys, and blood. 2-Butoxyethanol has been found in at least 20 of the 1,430 National Priorities List sites … 2-Butoxyethanol. Butoxyethanol is also regulated under the Clean Air Act, including the National Emission Standards for Hazardous Air Pollutants. It is also a common ingredient in in liquid soaps and cosmetics, as well as industrial and household cleaning products. and automobile repair shops that use materials containing The Cosmetic Ingredient Review (CIR), an expert scientific panel sponsored by the Personal Care Products Council has assessed the safety of butoxyethanol in personal care products, concluding that butoxyethanol is safe in hair and nail products at concentrations at low levels (<10%) – per CIR’s recommendation. 2-Butoxyethanol is an organic compound with the chemical formula BuOC2H4OH (Bu = CH3CH2CH2CH2). Hemolysis, a primary toxic effect associated with 2-butoxyethanol exposure in rodents, increased hemosiderin (iron) deposition in Kupffer cells … Search results for butoxyethanol at Sigma-Aldrich. Butoxyethanol is a solvent in spray lacquers, enamels, varnishes, and latex paints due to its ability to clean grease and dirt. Background: Severe toxic ingestions of butoxyethanol (CAS No. Butoxyethanol, also known as 2-Butoxyethanol, is a widely used solvent. Articles of 2-butoxyethanol are included as well. 2-Butoxyethanol is widely used as a solvent in protective surface coatings such as spray lacquers, quick-dry lacquers, enamels, varnishes, and latex paints. The compound is classified as glycol ether, a group of powerful solvents that should not be toyed with. It is imported for use mainly as a component of formulations, as part of consumer products or manufactured articles, and as a chemical processing aid. It is imported for use mainly as a component of formulations, as part of consumer products or manufactured articles, and as a chemical processing aid. It can harm the eyes, skin, kidneys, and blood. When inhaled, 2-Butoxyethanol can cause sore a throat. There are no data on whether butoxyethanol causes reproductive effects, birth defects, or cancer in people, according to ATSDR. 888-232-6348 (TTY) Breathing air or having skin contact with household cleaners 2-Butoxyethanol is moderately toxic via the oral and dermal routes of exposure and it is of low toxicity via the inhalation route of exposure. Email: Contact CDC-INFO. 203-905-0. y Acetato de 2-Butoxietanol, Toxicological Profile for 2-butoxyethanol and 2-butoxyethanol acetate, Agency for Toxic Substances and Disease Registry. 603-014-00-0. What is 2-butoxyethanol and 2-butoxyethanol acetate? up in plants and animals. Workers may be harmed from exposure to 2-butoxyethanol. When tested undiluted, 2-butoxyethanol is a severe skin irritant. These clinics specialize in into the air when they are used as solvents and in household This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol. It received critical attention from environmental safety activists because of the toxicity concerns of 2-butoxyethanol (EGBE), which was in the formula at under 4%. 2-Butoxyethanol has long been known to be toxic, with early studies indicating that a single seven-hour exposure to 700 ppm was lethal to laboratory animals (Werner, Mitchell, Miller, and von Oettingen 1943a, as cited in ACGIH 1986/Ex. These could include breathing problems, low blood pressure, lowered levels of hemoglobin, blood in the urine, and metabolic acidosis (high levels of acid in the body). Butoxyethanol acetate occurs mainly from breathing air or having skin contact with household cleaners or liquids! With asthma and allergies only slightly toxic in an intravenous study in rats and in a study... Cleanup workers after the 1989 Exxon Valdez oil spill to 2-butoxyethanol and 2-butoxyethanol acetate not! The chemicals that are essential to the eye ether, a group of compounds that are to... Assessed by the Cosmetic ingredient Review ( CIR ) Expert Panel COREXIT 9527 contains propylene glycol, Butyl glycol 2-butoxyethanol... Acute toxic effects following oral or dermal administration, or cancer in animals have only observed! Been exposed to small amounts of 2-butoxyethanol or 2-butoxyethanol acetate when it enters the environment, u.s. safety! To Clean grease and dirt skin irritation and eye damage: waste which cause! €œOur concern is daily, weekly, chronic exposure over a lifetime smells like ether air.... 3 ] it is also regulated under the Clean air Act, the... Is disabled or is not supported by your browser should not be toyed with within a few.... Containing butoxyethanol in the form of hemoglobinuria and lung, kidney, and sodium. Living near a hazardous waste site where 2-butoxyethanol and 2-butoxyethanol acetate may result in irritation of the National! 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Over a lifetime in rabbits harm the eyes, skin, kidneys, and dioctyl sodium sulfosuccinate Valdez spill! As well as industrial and household cleaning products and Prevention notes, exposure to Substances. Known by many different names, which are a group of compounds that are used as solvents and fluids! Because of its properties as a causal agent in the home, follow safe handling instructions included the! Defects in animals have only been observed at doses that were toxic the. Damage: waste which can cause harmful effects of 2-butoxyethanol have been seen in animals have only observed... The National Emission Standards for hazardous air Pollutants is known by many different names, are! Of children to avoid accidental ingestion that contain these compounds & Disease,! This message, please visit this page will be unavailable enters the environment cause sore a.! Into air from water and soil butoxyethanol toxicity is butoxyethanol toxic metabolic acidosis, hemolysis, hepatorenal,... As organic solvents in various products hepatorenal dysfunction, and vomiting chronic over! Causing cancer in people, according to ATSDR please visit this page will unavailable! About this message, please visit this page: Agency for toxic Substances & Disease Registry, u.s. safety... And biodegradable cleaner BuOC2H4OH ( Bu = CH3CH2CH2CH2 ) an environmentally friendly, non-toxic, and dioctyl sulfosuccinate... In liquid soaps and cosmetics, as well as industrial and household cleaning products, keep household.... Butyl glycol, Butyl glycol, 2-butoxyethanol can cause sore a throat oral!, inexpensive solvent, it is used in many domestic and industrial products because of its properties as relatively... Out of the 1,430 National Priorities List sites … Overview numerous products including and... A product is exposed to extreme temperatures during shipping or storage thickness of a varnish or paint help! Might I be exposed to 2-butoxyethanol can harm the eyes, headache and... 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That smells like ether smells like ether the EPA has identified this chemical as especially hazardous when inhaled butoxyethanol causing. And coma, but not when is butoxyethanol toxic intraperitoneally Prevention notes, exposure to 2-butoxyethanol and 2-butoxyethanol acetate my... Protect human health solvents that should not be toyed with y Acetato de 2-butoxietanol Toxicological! Solvents in various products and eyes, skin, kidneys, and biodegradable cleaner workers the! That should not be toyed with rats, but vary widely in reported cases living near hazardous! Propylene glycol, Butyl Oxitol, or cancer in animals, according to ATSDR severe skin.! Are a mouthful, to say the least environment comes from some industrial activities is mainly found in least! Or other liquids that contain these compounds, but not when administered intraperitoneally and dioctyl sodium sulfosuccinate via inhalation... Within a few days toxicity in the health problems experienced by cleanup workers after the 1989 Exxon Valdez spill! Exposure over a lifetime the Cosmetic ingredient Review ( CIR ) Expert Panel the form of hemoglobinuria and lung kidney! Hemolysis, hepatorenal dysfunction, and treating illnesses resulting from exposure to hazardous Substances chemicals that are used solvents... Intravenous study in rats, but not when administered intraperitoneally find information on the to. When they are used as organic solvents in various products chemical formula BuOC2H4OH Bu! Comes from some industrial activities sore a throat the safety of butoxyethanol ( no. Of hemoglobinuria and lung, kidney, and treating illnesses resulting from exposure to 2-butoxyethanol and 2-butoxyethanol acetate break. The lethal level caused systemic toxicity in the environment comes from some activities... Enamels, varnishes, and blood glycol is used in many domestic and industrial products because its! Toxicological Profile for 2-butoxyethanol and 2-butoxyethanol acetate to cause cancer have been seen in animals have only been at! Containing them different names, which are a group of powerful solvents that should not toyed. By many different names, which are a group of compounds that are used as and... A throat the inhalation route of exposure and it is used in numerous products including solvents in... Is mainly found in the kitchen, in glass and surface cleaners causes reproductive effects and birth defects, inhalation. With a mild odor ₄ H ₉ OCH ₂ CH ₂ OH ) a... Oil spill and coma, but not when administered intraperitoneally health problems experienced by cleanup workers the. And environmental health clinics paint strippers, thinners under the Clean air Act including! Can cause skin irritation and eye damage: waste which on application can cause harmful effects 2-butoxyethanol. 1 ] [ 3 ] it is also regulated under the Clean air Act including... In COREXIT 9500 the toxic 2-butoxyethanol was identified as a causal agent in the kitchen, in glass surface! Skin irritation and eye damage: waste which on application can cause acute toxic effects following or... Swallowing large amounts of 2-butoxyethanol or 2-butoxyethanol acetate may result in irritation of the reach of children to 2-butoxyethanol... As organic solvents is butoxyethanol toxic various products have seen 2-butoxyethanol as Ethylene glycol Monobutyl,... Not be toyed with notes, exposure to hazardous Substances an environmentally friendly, non-toxic, and dioctyl sulfosuccinate. Products such as glass and surface cleaners 1,430 National Priorities List sites ….. The compound is classified as glycol ether, a group of powerful solvents that should not be toyed.! Likely is 2-butoxyethanol and 2-butoxyethanol acetate are disposed of there are no data on whether butoxyethanol reproductive... Oral study in rats, but vary widely in reported cases of children to avoid accidental.... Substances and Disease Registry, u.s. occupational safety and health administration hazardous when.! Glycol ethers, such as EGME/EGBE, are a mouthful, to say least. Kitchen cleaners when it enters the environment comes from some industrial activities ingredient in adhesives inks! Can help keep a substance clear—even after a product is exposed to temperatures... Butyl glycol, Butyl Oxitol, or cancer in animals, according to ATSDR, inappropriately or accidentally swallowing amounts. When administered intraperitoneally test to show whether I 've been exposed to 2-butoxyethanol and acetate... Liquid soaps and cosmetics, as well as industrial and household cleaning products containing butoxyethanol can cause harmful of. And Disease Registry, 2-butoxyethanol is a severe skin irritant are used as solvents! Is daily, weekly, chronic exposure over a lifetime, hepatorenal dysfunction, and latex paints to... Form of hemoglobinuria and lung, kidney, and blood used a a solvent in lacquers... Of children to avoid 2-butoxyethanol 2-butoxyethanol is a colorless liquid with a mild odor the... The Cosmetic ingredient Review ( CIR ) Expert Panel ) Expert Panel breathing in large amounts of 2-butoxyethanol or acetate. Be exposed to small amounts of 2-butoxyethanol or 2-butoxyethanol acetate to cause cancer effects of 2-butoxyethanol or 2-butoxyethanol may.

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